Hysteretic behavior of bladder afferent neurons in response to changes in bladder pressure
نویسندگان
چکیده
منابع مشابه
Role of afferent neurons in stress induced degenerative changes of the bladder.
PURPOSE We investigated the role of afferent C fibers in morphological changes of the rat bladder during stress. MATERIALS AND METHODS Wistar albino rats were exposed to cold immobilization stress. Different routes of capsaicin administration before cold immobilization stress were studied. Capsaicin was given to neonates, around the vagus (perivagal) or celiac (periceliac), or perivagal plus ...
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The properties of bladder afferent neurons in L6 and S1 dorsal root ganglia of adult rats were evaluated after chronic bladder inflammation induced by 2 week treatment with cyclophosphamide (CYP; 75 mg/kg). Whole-cell patch-clamp recordings revealed that most (70%) of the dissociated bladder afferent neurons from control rats were capsaicin sensitive, with high-threshold long-duration action po...
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Maryam Argungu, Saziye Bayram, Bindi Brook, Buddhapriya Chakrabarti, Richard H Clayton, Donna M Daly, Rosemary J Dyson, Craig Holloway, Varun Manhas, Shailesh Naire, Tom Shearer, and Radostin Simitev Department of Bioengineering, Imperial College London, London, UK Department of Mathematics, SUNY Buffalo State, Buffalo NY, USA School of Mathematical Sciences, University of Nottingham, Nottingha...
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Background and aims: Bladder cancer is the most common tumor of the urinary tract and the ninth cancer in terms of incidence in both sexes in the world. Bladder cancer is the second most common cancer among men in Iran. The most important risk factors which attribute to the incidence of bladder cancer are tobacco usage, exposure to industrial materials, and chronic infection by Schistsoma. This...
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Nerve growth factor (NGF) has been proposed as an important mediator inducing bladder overactivity under pathological conditions such as spinal cord injury, bladder outlet obstruction, or cystitis. We therefore examined the effects of chronic NGF treatment on bladder activity and the properties of bladder afferent neurons. In adult female rats, NGF (2.5 microg/microl) was infused continuously i...
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ژورنال
عنوان ژورنال: BMC Neuroscience
سال: 2016
ISSN: 1471-2202
DOI: 10.1186/s12868-016-0292-5